On the rsv and most twins the rear cylinder tends to be run a bit richer because it has no direct airflow and the richer mixture makes it run a little cooler. If you just use a vac guage you will get it ballpark and it will run probably fine but a bit warm on the rear cylinder as you will probably mess with the stagger. On twins and espeicially on the rsv (even mentioned in the service manual) CO takes priority over vac, but by vac only is not gonna cause you a problem if you don't mind your nads being a touch warmer. You will probably notice the running temp might go up a bit on later bikes as the temp reading is taken from the rear cylinder, on early bikes from the front.