I'm with Legs, you could mix to match the two, but the question would be for what reason? I can understand running two different compounds of the 002 together (soft front, medium rear for example), but i'm not convinced i'd go for mixing an 002 with an 016, since effectively you will be running a front that will have a different operating heat range than the rear which could lead to some interesting handling moments on the road......
I guess the definitive answer would be to call Bridgestone and see what they say Matt :thumbup
As a side note, i've read plenty that with 'spirited' riding you'll see the 002 disappear in 1000-1500 miles.....