Service interval is 10k km, about 6250 miles, or annual.
Liz's 07 just had the first one, cost about £125 inc oils etc.
I think they need the valve clearances checking at about 10k on the later motors, that'll cost about £100 in labour.
Bits to watch for - look behind brake/gear levers for crash damage, clocks can fog up a bit. Keep it on an optimate or similar when not in use - the starter motor needs a fully charged battery to spin those dustbin sized pistons over and still manage a spark.
Replace the rear shock with an Ohlins or equivalent unit, the standard Sachs unit is a real POS. Whilst you are at it get some link plates from AF1 and swap them out too.
Back brake is a Factory order option, only available on the bike in it's Moldavia specification. It's a common source of complaint, it's tiny and often needs bleeding, which is very tricky to do properly. It's kind of redundant - there is masses of engine braking from the Rotax mill.
The bikes are very reliable, Falco's with 100k plus are not rare. Electrics are a bit weak - it IS Italian, but much better than a Duc. Build quality on the new Tuono model is very good, better than the Tuoldo IMHO.
Oil changes, brake pads, chains etc, very easy to do, engine a bit trickier. Frame has a lot of fixings that need service tools, so either invest or use a dealer.
Tank range isn't massive - 18 litre (allegedly) will only go to 100~120 miles before the warning light comes on, if you are caning it, 80 miles or less.
Other recommendations - it should have a set of Akra cans with it - they were free last year. Fit R&G bungs - especially to the rear engine mounts - it'll save the bike in a topple. Ermax screen is the best one in the UK, the stock item is a bit of a joke.